Alzheimer's disease progression model using disability assessment for dementia scores from bapineuzumab trials
نویسندگان
چکیده
منابع مشابه
Orbitofrontal Dysfunction Discriminates Behavioral Variant Frontotemporal Dementia from Alzheimers Disease
Background: Behavioral variant frontotemporal dementia (bvFTD) patients show prefrontal cortex dysfunction and atrophy. Methods: We investigated whether executive function in conjunction with prefrontal cortex atrophy discriminates bvFTD and Alzheimer’s disease (AD) patients efficiently at presentation. Results: AD and bvFTD patients were distinguishable by 89.5% on their performance of 3 execu...
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INTRODUCTION Alzheimer’s disease (AD) is the most common form of dementia, characterized by a gradual decline in cognitive functioning and memory.1 Approximately 5.4 million Americans are affected by this illness. Thirteen percent of persons 65 years of age and older have AD, with 1,275 new cases per 100,000 patients (65 years of age and older) reported annually.2 Advanced age is found to be th...
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The Gaussian Mixture Model Universal Background Model (GMM-UBM) approach is used to assess the Parkinson’s disease (PD) progression per speaker. The disease progression is assessed individually per patient following a user modelingapproach. Voiced and unvoiced segments are extracted and grouped separately to train the models. Additionally, the Bhattacharyya distance is used to estimate the diff...
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BACKGROUND Alzheimer's disease (AD) is a globally prevalent neurodegenerative condition, clinically characterized by progressive memory loss and gradual impairment of cognitive functions. Bapineuzumab is a fully humanized monoclonal antibody that binds to neurotoxic amyloid proteins in the brain, enhancing their clearance. We performed this systematic review and meta-analysis to evaluate the sa...
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ژورنال
عنوان ژورنال: Alzheimer's & Dementia: Translational Research & Clinical Interventions
سال: 2015
ISSN: 2352-8737
DOI: 10.1016/j.trci.2015.06.005